Magnesium Glycinate: My Lifeline for Sleep and Anxiety

It's about time for a damn good night sleep!

10/17/20253 min read

a hand holding two pills in the dark
a hand holding two pills in the dark

I’ve been a terrible sleeper since I was a child. Nights of tossing and turning, staring at the ceiling, and watching the hours tick by were normal for me. But as I got older, my sleep issues didn’t just leave me tired—they made my anxiety spiral. When I can’t sleep, my mind races, I replay conversations, imagine worst-case scenarios, and by the time morning comes, my anxiety feels 10 times worse and I am cranky B. It’s a vicious cycle: anxiety makes it hard to sleep, lack of sleep amplifies anxiety, and the spiral continues.

Why I Tried Magnesium Glycinate

After years of struggling, I started researching natural ways to calm my mind and improve sleep. That’s when I found magnesium glycinate—a highly absorbable form of magnesium paired with glycine, an amino acid known to promote relaxation. Unlike other magnesium supplements, it’s gentle on the stomach and may support neurotransmitters that help regulate mood and sleep.

Finding Reliable Information Matters

Before trying anything, I learned how important it is to get information from valid sources, specifically double-blind clinical trials—the gold standard in research. There’s a lot of hype out there, and while it’s okay to go down the “snake oil” rabbit hole (don't give in!) most unproven supplements just waste your money. Knowing which treatments are proven and effective makes the trial-and-error process much less frustrating.

What the Science Says

A 2025 randomized, double-blind, placebo-controlled trial looked at magnesium bisglycinate (a form of magnesium glycinate) for adults with poor sleep. The study involved 155 adults aged 18–65. Those taking 250 mg of magnesium bisglycinate daily for four weeks reported improvements in insomnia symptoms compared to the placebo group. While the effect was modest (Cohen’s d = 0.2), it was meaningful for people struggling with chronic sleep issues. ([pmc.ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412596/))

Sleep After Kids: A Whole New Level

Then I had kids. Suddenly, sleep became not just elusive, but complicated in entirely new ways. Between hormonal shifts, middle-of-the-night feedings, and the anxiety of being responsible for tiny humans, my body went on hyper-alert mode. I would lie in bed, listening to their breathing like a psychopath, analyzing every creak and sigh, terrified to miss anything. The lack of sleep compounded my anxiety in ways I didn’t think were possible. Magnesium glycinate helped a bit, but it wasn’t magic—it just gave me a little more resilience during nights that would have otherwise completely derailed me. I'll get to post partum depression another time, that one's a novel.

My Experience

I initially started with 200 mg tablets each night, taken about 30 minutes before bed. After a few weeks, I switched to the dropper liquid form, and I found it worked better for my body. Why? I honestly don’t know. I think every body is different, and sometimes it’s a matter of experimenting to find what helps you personally.

Even with magnesium glycinate, this is not a one-stop fix. Lack of sleep comes from a multitude of factors—stress being the biggest culprit for me. To really improve sleep and manage anxiety, I actively practice meditation, deep breathing, and redirecting my thoughts at night. Combining these strategies with magnesium helps me find more balance, but it’s a process.

Why It Works for Anxiety and Sleep

Magnesium helps regulate the nervous system and supports GABA, a neurotransmitter that calms brain activity. Glycine, the amino acid in magnesium glycinate, also promotes relaxation. Together, they help quiet the mental chatter that can make sleepless nights feel impossible

Things to Keep in Mind

Magnesium glycinate isn’t a cure-all. It works best alongside strategies that address the root causes of poor sleep, like stress management, routine, and mindfulness. Always consult a healthcare provider before starting a supplement, especially if you take medications or have underlying health issues.

So...

For me, magnesium glycinate—especially in liquid dropper form—has been a gentle yet effective tool to break the cycle of sleepless nights and amplified anxiety. While results vary, it’s worth experimenting to see what works for your body. Again, I’m no doctor, just a normal person sharing my experience. The combination of supplement, stress management, and self-care has made a noticeable difference in how I sleep and manage my anxiety.

Note: This reflects my personal experience and is not medical advice. Consult a healthcare professional before changing your health regimen.

XO,

Alyssa